Table 1.

Clinical and pathologic characteristics

CharacteristicsMGZLcHLPMBL
Total patients201817
Male gender15 (75%)8 (44%)10 (59%)
Median age (years)342833
 Age range17–7719–7217–52
Mediastinal tumor present16/17a (94%)18 (100%)17 (100%)
Pretreatment biopsy18/18b (100%)15/18 (83%)17/17 (100%)
MGZL Tumor morphology
 PMBL-Like5/20 (25%)NANA
 cHL-Like5/20 (25%)NANA
 Composite PMBL/cHL-like1/20 (5%)NANA
 Intermediate9/20 (45%)NANA
Immunophenotype
 CD2019/20 (95%)3/16 (19%)17 (100%)
 CD3020/20 (100%)18/18 (100%)12/14 (85%)
 CD1516/20 (80%)17/18 (95%)1/11 (9%)
 EBER in situ hybridization0/11 (0%)NANA
Percent tumor cell quartiles
 <253/17 (18%)8/18 (44%)3/17 (18%)
 25–504/17 (23.5%)7/18 (39%)3/17 (18%)
 50–756/17 (35%)2/18 (11%)2/17 (12%)
 75–1004/17 (23.5%)1/18 (6%)9/17 (53%)
  • Abbreviation: NA, not applicable.

  • aThree cases unknown.

  • bTwo cases unknown.