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Volume 2, Issue 1, pp. 70-91
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History
- Received December 5, 2019
- Revision received October 6, 2020
- Accepted October 28, 2020
- Published first November 2, 2020.
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©2020 American Association for Cancer Research.
Author Information
- Ruth Flümann1,2,3,4,#,
- Tim Rehkämper1,2,3,4,#,
- Pascal Nieper1,2,3,4,#,
- Pauline Pfeiffer1,2,3,4,
- Alessandra Holzem1,2,3,4,
- Sebastian Klein5,
- Sanil Bhatia6,
- Moritz Kochanek1,2,3,4,
- Ilmars Kisis1,2,3,4,
- Benedikt W. Pelzer1,2,3,4,
- Heinz Ahlert6,
- Julia Hauer7,8,
- Alexandra da Palma Guerreiro1,2,4,
- Jeremy A. Ryan9,
- Maurice Reimann10,
- Arina Riabinska1,2,3,4,
- Janica Wiederstein4,
- Marcus Krüger4,
- Martina Deckert2,11,
- Janine Altmüller12,
- Andreas R. Klatt13,
- Lukas P. Frenzel1,2,4,
- Laura Pasqualucci14,
- Wendy Béguelin15,
- Ari M. Melnick15,
- Sandrine Sander16,
- Manuel Montesinos-Rongen2,11,
- Anna Brunn2,11,
- Philipp Lohneis2,3,5,
- Reinhard Büttner2,3,5,
- Hamid Kashkar3,4,17,
- Arndt Borkhardt6,
- Anthony Letai9,
- Thorsten Persigehl2,18,
- Martin Peifer2,3,19,
- Clemens A. Schmitt10,20,
- Hans Christian Reinhardt21,##,* and
- Gero Knittel1,2,3,4,##
- 1University of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic I of Internal Medicine, Cologne, Germany.
- 2Center for Integrated Oncology, University of Cologne, Cologne, Germany.
- 3Center for Molecular Medicine, University of Cologne, Cologne, Germany.
- 4Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
- 5Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Cologne, Germany.
- 6Medical Faculty, Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
- 7Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
- 8National Center for Tumor Diseases (NCT), Dresden, Germany.
- 9Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
- 10Charité Universitätsmedizin Berlin, Medical Department of Hematology, Oncology and Tumor Immunology, and Molekulares Krebsforschungszentrum - MKFZ, Virchow Campus, Berlin, Germany.
- 11Faculty of Medicine and University Hospital Cologne, Institute of Neuropathology, University of Cologne, Cologne, Germany.
- 12Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
- 13Faculty of Medicine and University Hospital Cologne, Institute of Clinical Chemistry, University of Cologne, Cologne, Germany.
- 14Department of Pathology and Cell Biology, Institute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York.
- 15Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, New York.
- 16Adaptive Immunity and Lymphoma Group, German Cancer Research Center/National Center for Tumor Diseases Heidelberg, Heidelberg, Germany.
- 17Faculty of Medicine and University Hospital Cologne, Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
- 18Faculty of Medicine and University Hospital Cologne, Department of Radiology and Interventional Radiology, University of Cologne, Cologne, Germany.
- 19Department of Translational Genomics, University of Cologne, Cologne, Germany.
- 20Kepler Universitätsklinikum, Medical Department of Hematology and Oncology, Johannes Kepler University, Linz, Austria.
- 21Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University Duisburg-Essen, German Cancer Consortium (DKTK Partner Site Essen), Essen, Germany.
- ↵*Corresponding Author:
Hans Christian Reinhardt, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany. Phone: 49-201-723-3136; Fax: 49-201-723-5961; E-mail: christian.reinhardt{at}uk-essen.de
January 2021
Volume 2, Issue 1
Volume 2, Issue 1
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities
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